รศ.ดร.นพ.ดำเนินสันต์ พฤกษากร

Dumnoensun Pruksakorn
Associate Professor,
M.D., Ph.D.

Contact Information

Dumnoensun Pruksakorn
Assoc. Prof,M.D., Ph.D.

Email :
dumnoensun@hotmail.com

Address :  Department of Orthopaedics ,
OMICS CENTER FOR HEALTH SCIENCES (OCHS),
Faculty of Medicine, Chiang Mai University,
Tel.   +66-53-945544.   Fax. +66-53-946442

Biography

Education & Training

1994  :   Graduate High School in Demonstration CMU (Second Class Honors).

2000 :   Degree of Doctor of Medicine (Second Class Honors).

2005 :   AOEA Junior Ambassador Fellowship Program,Singapore General Hospital, Singapore.

2006 :   Certificate of Proficiency in Orthopedic Surgery, Thai Orthopedic Association, Medical Council, Thailand

2008 :   Visiting fellowship of Muskuloskeletal Oncology Surgery, Munster University Hospital, Munster, Germany.

2010 :   Visiting PhD student. Massachusette Institutue of Technology (MIT), Cambridge, Massachusette, USA

2010 :   Philosophy of Doctor in “Apply Biological Science Program” at Chulabhorn Graduated Institute, Bangkok, Thailand.

2011 :   Clinical fellowship of Musculoskeletal Oncology and Lower Limb  Reconstruction, University of British Columbia, Canada

Experience

1999 :   The joint Program of academic exchange, Nippon Medical School, Japan.

2005 :   The Cartilage Engineering in Clinical Application Program Academy of Sciences of The Czech Republic.

2009 :   Good Clinical Practice training

Honors and Achievements:

1996 :   Bronze medal of Academic Performance.

2000 :    Head of Medical Student Committee.

2001 :   Bronze medal of Academic Performance.

2001 :   Second Class Honors in MD.

2002 :   Head of Chiang Mai University Bachelors Committee. Tokyo

2004 :   Head of The Resident Training, Faculty of medicine, Chiang Mai University.

2005 :   Second-best Resident Paper Contest in 27th Annual Meeting of The Royal College of Orthopedic Surgeons of Thailand

Research & Publications

Publications : 

    • Pruksakorn D, Sananpanich K, Khunamornpong S, Chalidapong P, Putijarernrat S. Posterior Approach Technique for Accessory-Suprascapular Nerve Transfer: A Cadaveric Study of the Anatomical Landmarks and Number of Myelinated Axons. Clin Anat. 2007 Mar; 20(2): 140-3.
    • Pruksakorn D, Thiranont N, Rujiwetpongstorn V. Ong-chai S, PothachareonP,Luevitoonvechkij S, Sugandhavesa N, Kongtawelert P.Age-related Changes of Chondroitin 6-Sulfate WF6 Epitope Level in Normal Human Serum. Chiang Mai Medical Bulletin. 2006 Dec; 45(4): 139-144
    • Pruksakorn D, Rojanasthien S, Pothachareon P, Luevitoonvechkij S, Wongtriratanachai P, Ong-chai S, , Kongtawelert P. Chondroitin Sulfate Epitope (WF-6) and Hyaluronan as Serum Markers of Cartilage Degeneration in Patients Following Anterior Cruciate Ligament Injury. Journal of Science and Medicine in Sport; June 2008 (Epub ahead of print)
    • Pruksakorn D, Khamwaen N, Pothacharoen P, Arpornchayanon O, Rojanasthien S, Kongtawelert P. Chondrogenic properties of primary human chondrocytes in hyaluronic acid treated gelatin scaffold. Journal Med Assoc Thai. 2009 April;92(4):483-90.
    • Nganvongpanit K, Pothacharoen P, Cherdchou P, Klunklin K, Warrit K, Settakorn J, Pattamapaspong N, Luevitoonvechkij S, Arpornchayanon O, Kongtawelert P, Pruksakorn D. Prospective evaluation of serum biomarker levels and cartilage repair by autologous chondrocyte transplantation and subchondral drilling in a canine model. Arthritis Research & Therapy; 2009 May26;11(3):R78.
    • Pruksakorn D, Lirdprapamongkol K, Chokchaichamnankit D, Subhasitanont P, Chiablaem K, Svasti J, Srisomsap C. Metabolic alteration of HepG2 in scaffold-based 3D culture: proteomic approach. Proteomics; 2010;10:3896-3904
    • Arpornchayanon O, Leerapun T, Sivasomboon C, Settakorn J, Sugandhavesa N, Pruksakorn D. Recurrent tibial intracortical osteosarcoma of a Thai patints: a case report. J Med Case Reports. 2011;5(1):93.
    • Limmahakhun S, Pothacharoen P, Theera-Umpon N, Arpornchayanon O, Leerapun T, Luevitoonvechkij S, Pruksakorn D. Relationships between Serum Biomarker Levels and Clinical Presentation of Human Osteosarcomas. Asian Pac J Cancer Prev. 2011;12(7):1717-22.2
    • Natesirinilkul R, Charoenkwan P, Chuansumrit A, Pruksakorn D, Visrutaratna P, Jutavijittum R, et al. Treatment of Severe Hemophilia A with High-titer Inhibitor by Plasma Exchange and Continuous Infusion of Recombinant Factor VIII : A Case Report. J Hematol Transfus Med. 2012;22:41-9.
    • Pruksakorn D, Pothachareoun P, Klunklin K, Nimkingratana P, Rojanastein S, Padongkiert S, et al. Articular Cartilage Injury Treatment: History and Basic Science Review. Orthopedic & Muscular System: Current Research. 2012 Jun 13;1(4).
    • Klangjorhor J, Nimkingratana P, Settakorn J, Pruksakorn D, Leerapun T, Arpornchayanon O, Rojanasthien S, Kongtawelert P, Pothacharoen P. Hyaluronan production and chondrogenic properties of primary human chondrocyte on gelatin based hematostatic spongostan scaffold. Journal of Orthopaedic Surgery and Research [Internet]. 2012;7(1)
    • Sangsin A, Pattamapaspong N, Settakorn J, Leerapun T, Pruksakorn D. Extraosseous osteosarcoma: A case report and review of the literature. Journal of the Medical Association of Thailand [Internet]. 2013;96(4):491-5.
    • Chionh YH, Ho C-, Pruksakorn D, Ramesh Babu I, Ng CS, Hia F, McBee ME, Su D, Pang YLJ, Gu C, Dong H, Prestwich EG, Shi P-, Preiser PR, Alonso S, Dedon PC. A multidimensional platform for the purification of non-coding RNA species. Nucleic Acids Res [Internet]. 2013;41(17)
    • Arpornchayanon O, Leerapun T, Pruksakorn D, Panichkul P. Result of extracorporeal irradiation and re-implantation for malignant bone tumors: a review of 30 patients. Asia Pac J Clin Oncol. 2013;9(3):214-9.
    • Wongtriratanachai P, Pruksakorn D, Pothacharoen P, Nimkingratana P, Pattamapaspong N, Phornphutkul C, Setsitthakun S, Fongsatitkul L, Phrompaet S. Autologous chondrocyte implantation for cartilage injury treatment in chiang mai university hospital: A case report. J Med Assoc Thai [Internet]. 2013;96(11):1518-22.
    • Pruksakorn D, Tirankgura P, Luevitoonvechkij S, Chamnongkich S, Sugandhavesa N, Leerapun T, Pothacharoen P. Changes in the serum cartilage biomarker levels of healthy adults in response to an uphill walk. Singapore Med J [Internet]. 2013;54(12):702-8.
    • Pattamapaspong N, Sivasomboon C, Settakorn J, Pruksakorn D, Muttarak M. Pitfalls in imaging of musculoskeletal infections. Semin Musculoskelet Radiol. 2014;18(1):86-100.
    • Pruksakorn D, Chantarapanich N, Arpornchayanon O, Leerapun T, Sitthiseripratip K, Vatanapatimakul N. Rapid-prototype endoprosthesis for palliative reconstruction of an upper extremity after resection of bone metastasis. International journal of computer assisted radiology and surgery. 2015;10(3):343-50.
    • Klangjorhor J, Phitak T, Pruksakorn D, Pothacharoen P, Kongtawelert P. Comparison of growth factor adsorbed scaffold and conventional scaffold with growth factor supplemented media for primary human articular chondrocyte 3D culture. BMC biotechnology. 2014;14:108.
    • Wanachewin O, Klangjorhor J, Pothacharoen P, Phitak T, Laohapoonrungsee A, Pruksakorn D, et al. The promoting effects of sesamin on osteoblast differentiation of human mesenchymal stem cells. Journal of Functional Foods. 2015;14(0):395-406.
    • Pruksakorn D, Leuvitoonvechakij S, Pothacharoen P, Mungmee C, Poomcharoen P, Leerapun T, et al. Diurnal variation of serum chondroitin sulfate WF6 and hyaluronic acid in the healthy, traumatic knee and the osteoarthritic knee. Journal of the Medical Association of Thailand = Chotmaihet thangphaet. 2015;98(1):45-52.322.
    • Sangsin A, Pruksakorn D, Luevitoonvechkij S, Pothacharoen P, Kongthaweelert P. Association between the severity of knee osteoarthritis and serum cartilage biomarker levels. Journal of the Medical Association of Thailand = Chotmaihet thangphaet. 2015;98(1):26-32.
    • Pruksakorn D, Leuvitoonvechakij S, Pothacharoen P, Mungmee C, Poomcharoen P, Leerapun T, Patumanond J. Diurnal variation of serum chondroitin sulfate WF6 and hyaluronic acid in the healthy, traumatic knee and the osteoarthritic knee.J Med Assoc Thai. 2015 Jan;98(1):45-52.
    • Theerathanagorn T, Klangjorhor J, Sakulsombat M, Pothacharoen P, Pruksakorn D, Kongtawelert P, Janvikul W.J. In vitro human chondrocyte culture on plasma-treated poly(glycerol sebacate) scaffolds.Biomater Sci Polym Ed. 2015;26(18):1386-401. doi: 10.1080/09205063.2015.1096446.
    • Pruksakorn D, Phanphaisarn A, Arpornchayanon O, Uttamo N, Leerapun T, Settakorn J.Survival rate and prognostic factors of conventional osteosarcoma in Northern Thailand: A series from Chiang Mai University Hospital.Cancer Epidemiol. 2015 Dec;39(6):956-63. doi: 10.1016/j.canep.2015.10.016.
    • Pruksakorn D, Phanphaisarn A, Pongnikorn D, Daoprasert K, Teeyakasem P, Chaiyawat P, Katruang N, Settakorn J. AgeStandardized Incidence Rates and Survival of Osteosarcoma in Northern Thailand. Asian Pac J Cancer Prev. 2016;17(7):3455-8.
    • Sriuttha W, Uttamo N, Kongkaew A, Settakorn J, Rattanasalee S, Kongtawelert P, Pruksakorn D, Pothacharoen P.Ex vivo and in vivo characterization of cold preserved cartilage for cell transplantation. Cell Tissue Bank. 2016 Dec;17(4):721- 734.
    • Pruksakorn D, Teeyakasem P, Klangjorhor J, Chaiyawat P, Settakorn J, Diskul-Na- Ayudthaya P, Chokchaichamnankit D, Pothacharoen P, Srisomsap C. Overexpression of KH-type splicing regulatory protein regulates proliferation, migration, and implantation ability of osteosarcoma. Int J Oncol. 2016 Sep;49(3):903-12. doi: 10.3892/ijo.2016.3601.
    • Siriwittayakorn W, Apornchayanon O, Lorsomradee S, Theera-Umpon N, Settakorn J, Pruksakorn D. Intra-lesional NSAIDs Injection: Unreported Treatment in (Extra- abdominal) Desmoid Tumors. THE BANGKOK MEDICAL JOURNAL. 2016;12.
    • Phanphaisarn A, Patumanond J, Settakorn J, Chaiyawat P, Klangjorhor J, Pruksakorn D. Prevalence and Survival Patterns of Patients with Bone Metastasis from Common Cancers in Thailand. Asian Pac J Cancer Prev. 2016;17(9):4335-4340.
    • Chaiyawat P, Settakorn J, Sangsin A, Teeyakasem P, Klangjorhor J, Soongkhaw A, Pruksakorn D. Exploring targeted therapy of osteosarcoma using proteomics data. Onco Targets Ther. 2017 Feb 1;10:565-577.
    • Srisuthtayanont W, Pruksakorn D, Kongtawelert P, Pothacharoen P, Effects of sesamin on chondroitin sulfate proteoglycan synthesis induced by interleukin-1beta in human chondrocytes. BMC Complement Altern Med. 2017 May 31;17(1):286.
    • Chaiyawat P, Klangjorhor J, Settakorn J, Champattanachai V, Phanphaisarn A, Teeyakasem P, Svasti J, Pruksakorn D, Activation Status of Receptor Tyrosine Kinases as an Early Predictive Marker of Response to Chemotherapy in Osteosarcoma. , Transl Oncol. 2017 Oct;10(5):846-853.
    • Phitak T, Boonmaleerat K, Pothacharoen P, Pruksakorn D, Kongtawelert P , Leptin alone and in combination with interleukin-1-beta induced cartilage degradation potentially inhibited by EPA and DHA. Connect Tissue Res. 2018 Jul;59(4):316-331.4
    • Chaiyawat P, Pruksakorn D, Phanphaisarn A, Teeyakasem P, Klangjorhor J, Settakorn J, Expression patterns of class I histone deacetylases in osteosarcoma: a novel prognostic marker with potential therapeutic implications. Mod Pathol. 2018 Feb;31(2):264-274.
    • Pruksakorn D, Lorsomradee S, Phanphaisarn A, Teeyakasem P, Klangjorhor J, Chaiyawat P, Kosachunhanun N, Settakorn J, Arpornchayanon O , Safety and efficacy of intralesional steroid injection for aggressive fibromatosis. World J Surg Oncol. 2017 Nov 2;15(1):195.
    • Vaseenon T, Saengsin J, Pattamapaspong N, Settakorn J, Pruksakorn D, Spindle Cell Hemangioma of the Midfoot: A Case Report. J Orthop Case Rep. 2017 Sep- Oct;7(5):75-79.
    • Vaseenon T, Saengsin J, Kaminta A, Pattamapaspong N, Settakorn J, Pruksakorn D, Ankle ligament reconstruction after wide resection of the osteosarcoma of the distal fibula: a case report. BMC Res Notes. 2017 Dec 28;10(1):769.
    • Pruksakorn D, Phanphaisarn A, Settakorn J, Arpornchayanon U, Tantraworasin A, Chaiyawat P, Klangjorhor J, Teeyakasem P , Prognostic score for life expectancy evaluation of lung cancer patients after bone metastasis. J Bone Oncol. 2017 Nov 3;10:1-5.
    • Pruksakorn D, Klangjorhor J, Lirdprapamongkol K, Teeyakasem P, Sungngam P, Chaiyawat P, Phanphaisarn A, Settakorn J, Srisomsap C , Oncogenic roles of serine- threonine kinase receptor-associated protein (STRAP) in osteosarcoma. Cancer Chemother Pharmacol. 2018 Dec;82(6):1039-1047.
    • Pruksakorn D, Kongthavonskul J, Teeyakasem P, Phanphaisarn A, Chaiyawat P, Klangjorhor J, Arpornchayanon O, Surgical outcomes of extracorporeal irradiation and re-implantation in extremities for high grade osteosarcoma: A retrospective cohort study and a systematic review of the literature. J Bone Oncol. 2018 Dec 10;14:100210.
    • Wongwichai T, Teeyakasem P, Pruksakorn D, Kongtawelert P, Pothacharoen P, Anthocyanins and metabolites from purple rice inhibit IL-1β-induced matrix metalloproteinases expression in human articular chondrocytes through the NF-κB and ERK/MAPK pathway. Biomed Pharmacother. 2019 Feb 20;112:108610.
    • Chaiyawat P, Sungngam P, Teeyakasem P, Sirikaew N, Klangjorhor J, Settakorn J, Diskul-Na-Ayudthaya P, Chokchaichamnankit D, Srisomsap C, Svasti J, Pruksakorn D , Protein profiling of osteosarcoma tissue and soft callus unveils activation of the unfolded protein response pathway. Int J Oncol. 2019 Feb 28.

Contact Us

Address:   9th – The 50th Anniversary Building, Faculty of Medicine, Chiang Mai University 110 Intawaroros Road, Si Phum, Muang, Chiang Mai 50200

Email :   dumnoensun@hotmail.com

Organizations: Department of Orthopaedics , OMICS CENTER FOR HEALTH SCIENCES (OCHS), Faculty of Medicine, Chiang Mai University, Chiang Mai , Thailand , 50200.

Tel. 66-53-945544.    Fax. 66-53-946442