Ranchana Yeewa, Ph.D.
Contact Information
Ranchana Yeewa, Ph.D.
Email : ranchana.y@cmu.ac.th
Address : Center of Multidisciplinary Technology for Advanced Medicine (CMUTEAM), 9th floor – The 50th Anniversary Building, Faculty of medicine, Chiang Mai University
Research Interests
Given a strong background in laboratory animals in biomedical research, I am interested in conducting experiments with transgenic animals that can recapitulate features of human diseases. Currently, I am developing a transgenic Drosophila model to gain insights into epigenetic regulation in human neurological disorders and aging. Taking advantage of working at CMUTEAM, I eventually included multi-omics approaches, such as transcriptomics and metabolomics, in my research studies. I surmise that this platform can be further interrogated to validate the observations in mammalian models including mouse or primary cells, which finally leads to novel medical breakthroughs for humans.
Expertise
- Molecular biology
- Biochemistry
- Animal models
- Aging/Age-related changes
Biography
Work experience
Nov 2022 – Present :
Researcher CMUTEAM, Faculty of Medicine, Chiang Mai University
Jun 2021 – Oct 2022 :
Assistant Researcher CMUTEAM, Faculty of Medicine, Chiang Mai University
Education
Ph.D. : 2015 – 2020
DOCTOR OF PHILOSOPHY (BIOCHEMISTRY) Department of Biochemistry, Faculty of Medicine, Chiang Mai University.
D.V.M. : 2009 – 2015
DOCTOR OF VETERINARY MEDICINE (FIRST CLASS HONORS) Faculty of Veterinary Medicine, Chiang Mai University.
Awards
27 – 28 July 2016 :
Certificate of Outstanding Award, Name of project: Effects of purple rice (Oryza sativa L. indica) fraction on prostate carcinogenesis. 14th Annual Biochemical Research Meeting. At Faculty of Medicine, Chiang Mai University, Thailand.
2015 :
Certificate of Honors Student in 2015, GPA 4.00, Faculty of Medicine, Chiang Mai University, Thailand.
Research & Publications
Research Interests
- Functional Genetics
- Neuroscience
- Metabolomics
- Animal models
Publications
- Yeewa R, Chaiya P, Jantrapirom S, Shotelersuk V, Lo Piccolo L. Multifaceted roles of YEATS domain-containing proteins and novel links to neurological diseases. Cellular and molecular life sciences. 2022 Mar 12;79(3):183.
- Sakuludomkan W, Yeewa R, Subhawa S, Khanaree C, Bonness AI, Chewonarin T. Effects of Fermented Houttuynia cordata Thunb. on Diabetic Rats Induced by a High-Fat Diet with Streptozotocin and on Insulin Resistance in 3T3-L1 Adipocytes. Journal of nutrition and metabolism. 2021 Aug 6;2021:6936025.
- Subhawa S, Naiki-Ito A, Kato H, Naiki T, Komura M, Nagano-Matsuo A, Yeewa R, Inaguma S, Chewonarin T, Banjerdpongchai R, Takahashi S. Suppressive Effect and Molecular Mechanism of Houttuynia cordata Thunb. Extract against Prostate Carcinogenesis and Castration-Resistant Prostate Cancer. Cancers. 2021 Jul 7;13(14):3403.
- Naiki-Ito, A., Kato, H., Naiki, T., Yeewa, R., Aoyama, Y., Nagayasu, Y., Suzuki, S., Inaguma, S. and Takahashi, S., 2020. A novel model of non-alcoholic steatohepatitis with fibrosis and carcinogenesis in connexin 32 dominant-negative transgenic rats. Archives of toxicology, 94(12), pp.4085-4097.
- Yeewa, R., Naiki-Ito, A., Naiki, T., Kato, H., Suzuki, S., Chewonarin, T., Takahashi, S., Hexane Insoluble Fraction from Purple Rice Extract Retards Carcinogenesis and Castration-Resistant Cancer Growth of Prostate through Suppression of Androgen Receptor Mediated Cell Proliferation and Metabolism. Nutrients, 2020; 12(2): 558.
- Yeewa, R., Sakuludomkan, W., Kiriya, C., Khanaree, C., Chewonarin, T. Attenuation of benign prostatic hyperplasia by hydrophilic active compounds from pigmented rice in a testosterone implanted rat model. Food & Function. 2020; 11(2): 1585-1598.
- Kiriya, C., Yeewa, R., Khanaree, C., Chewonarin, T. Purple rice extract inhibits testosterone‐induced rat prostatic hyperplasia and growth of human prostate cancer cell line by reduction of androgen receptor activation. Journal of food biochemistry. 2019; 43(9): e12987.
- Tiwananthagorn S., Kato H., Yeewa, R., Muengpan A., Polseela R. and Leelayoova S. Comparison of LAMP and PCR for molecular mass screening of sand flies for Leishmania martiniquensis infection. Mem Inst Oswaldo Cruz. 2017; 112(2): 100–107.