Wasinee Wongkummool, Ph.D.
Contact Information
Wasinee Wongkummool, Ph.D.
Email :
wasinee.won@cmu.ac.th
wong.wasinee@gmail.com
Address : Center of Multidisciplinary Technology for Advanced Medicine (CMUTEAM), 9th floor – The 50th Anniversary Building, Faculty of medicine, Chiang Mai University
Research Interests
My research interests primarily focus on the development and application of induced pluripotent stem cells (iPSCs) as a versatile platform for disease modeling, molecular and functional studies, and mechanism investigations. The main goal of my research is to establish robust iPSC-based systems that facilitate drug screening for neurological disorders, ultimately contributing to advancements in therapy and personalized medicine in this field.
Another crucial aspect of my research centers on genetic engineering, with a specific emphasis on harnessing the CRISPR/Cas9 system for precise genetic modifications. Through innovative genetic engineering techniques, I aim to gain deeper insights into disease mechanisms and explore potential therapeutic targets for various medical conditions.
By combining these interdisciplinary areas of focus, I aspire to make significant contributions to improving healthcare outcomes for patients with neurological disorders and contribute to the advancement of medical research, particularly in the development of novel therapeutic approaches.
Expertise
- Stem cell research
- Gene editing
- CRISPR (CRISPR/Cas9) system
- Molecular and cellular biology
- Molecular genetics
- Cell culture
- Laboratory skills
Biography
Work experience
Feb 2023 – present :
ASSISTANT RESEARCHER Center of Multidisciplinary Technology for Advanced Medicine (CMUTEAM) Faculty of Medicine Chiang Mai University, Thailand
Sep 2021 – Aug 2022 (1 year) :
POSTDOCTORAL RESEARCHER Department of Pediatrics Faculty of Medicine Ramathibodi Hospital Mahidol University, Thailand
Sep 2020 – Aug 2021 (1 year) :
POSTDOCTORAL RESEARCHER Stem Cells Research Unit Institute of Molecular Biosciences Mahidol University, Thailand
Apr 2017 – Oct 2021 (7 months) :
VISITING SCHOLAR Department of Cell and Developmental Biology, University of Michigan Medical School, USA
Education
Ph.D. : 2013 – 2020
Doctor of Philosophy (Medical Biochemistry and Molecular Biology) Faculty of Medicine Siriraj Hospital (International Program) Mahidol University, Thailand
B.Sc. : 2009 – 2012
Bachelor of Science (Medical Technology) Faculty of Associated Medical Sciences Chiang Mai university, Thailand
Current Projects
- Functional genetic characterization of a variant of unknown significance affecting the FAME4- associating gene by CRISPR/Cas9-based cell model
- Advancing Therapeutic Screening in Drug-Resistant Epilepsy through the Development of a Patient-Derived Induced Pluripotent Stem Cell (iPSC) Genetic Platform
Research & Publications
Research Interests
My research interests primarily focus on the development and application of induced pluripotent stem cells (iPSCs) as a versatile platform for disease modeling, molecular and functional studies, and mechanism investigations. The main goal of my research is to establish robust iPSC-based systems that facilitate drug screening for neurological disorders, ultimately contributing to advancements in therapy and personalized medicine in this field.
Another crucial aspect of my research centers on genetic engineering, with a specific emphasis on harnessing the CRISPR/Cas9 system for precise genetic modifications. Through innovative genetic engineering techniques, I aim to gain deeper insights into disease mechanisms and explore potential therapeutic targets for various medical conditions.
By combining these interdisciplinary areas of focus, I aspire to make significant contributions to improving healthcare outcomes for patients with neurological disorders and contribute to the advancement of medical research, particularly in the development of novel therapeutic approaches.
Publications
- Wongkummool W, Tong-Ngam P, Munkongdee T, Tangprasittipap A, Paiboonsukwong K, Hongeng S, et al. Generation of human induced pluripotent stem cell line (MUi034-A) from an unusual case of hydrops fetalis associated with homozygous hemoglobin Constant Spring. Stem Cell Res. 2022;65:102979.
- Pongpaksupasin P, Wongkummool W, Tong-Ngam P, Jearawiriyapaisarn N, Paiboonsukwong K, Sangkitporn S, et al. A generation of human-induced pluripotent stem cell line (MUi032-A) from a Choroideremia disease patient carrying a hemizygous mutation on the CHM gene. Stem Cell Res. 2022;65:102964.
- Maneepitasut W, Wongkummool W, Thong-ngam P, et al. Generation of human induced pluripotent stem cell line (MUi026-A) from a patient with autosomal dominant polycystic kidney disease carrying PKD1 point mutation. Stem Cell Res. 2021 Mar. doi: 10.1016/j.scr.2021.102306.
- Wongkummool W, Maneepitasut W, Thong-ngam P, et al. Establishment of MUi009-A human induced pluripotent stem cells from a 32 year old male with homozygous β0-thalassemia coinherited with heterozygous alpha-thalassemia 2. Stem Cell Res. 2017 Mar 7. doi: 10.1016/j.scr.2017.02.012.
- Wongkummool W, Maneepitasut W, Munkongdee T, et al. Derivation of the human induced stem cell line MUi017-A from a patient with homozygous Hemoglobin Constant Spring. Stem Cell Res. 2017 Mar 7. doi: 10.1016/j.scr.2017.02.014.
- Tangprasittipap A, Jittorntrum B, Wongkummool W, et al. Generation of induced pluripotent stem cells from peripheral blood CD34+ hematopoietic progenitors of a 31year old healthy woman. Stem Cell Res. 2017 Mar 7. doi: 10.1016/j.scr.2017.02.013.
Contact Us
Address : 9th floor – The 50th Anniversary Building, Faculty of Medicine, Chiang Mai University, 110 Intawaroros Road, Si Phum, Muang, Chiang Mai 50200
Email : wasinee.won@cmu.ac.th, wong.wasinee@gmail.com
Organizations : Center of Multidisciplinary Technology for Advanced Medicine (CMUTEAM)